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Glycopeptide enkephalin analogues produce analgesia in mice: evidence for penetration of the blood-brain barrier.

Most peptides have not proved useful as neuroactive drugs because they are blocked by the blood-brain barrier and do not reach their receptors within the brain. Intraperitoneally administered L-serinyl beta-D-glucoside analogues of [Met5]enkephalin (glycopeptides) have been shown to be transported a...

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Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Polt, R, Porreca, F, Szabò, L Z, Bilsky, E J, Davis, P, Abbruscato, T J, Davis, T P, Harvath, R, Yamamura, H I, Hruby, V J
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 1994
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44349/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8041755/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.15.7114
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