Intercellular chaperone transmission via exosomes contributes to maintenance of protein homeostasis at the organismal level

The heat shock response (HSR), a transcriptional response that up-regulates molecular chaperones upon heat shock, is necessary for cell survival in a stressful environment to maintain protein homeostasis (proteostasis). However, there is accumulating evidence that the HSR does not ubiquitously occur...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Takeuchi, Toshihide, Suzuki, Mari, Fujikake, Nobuhiro, Popiel, H. Akiko, Kikuchi, Hisae, Futaki, Shiroh, Wada, Keiji, Nagai, Yoshitaka
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4434695/
https://ncbi.nlm.nih.gov/pubmed/25918398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1412651112
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