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Can "big" insulin-like growth factor II in serum of tumor patients account for the development of extrapancreatic tumor hypoglycemia?

The pathogenesis of extrapancreatic tumor hypoglycemia has been related to the secretion of big insulin-like growth factor (IGF) II by the tumor. In 25 of 28 patients with this type of hypoglycemia we found 1.5-8-fold elevated serum levels of immunoreactive big (15-25 kD), but decreased levels of no...

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Bibliografiset tiedot
Julkaisussa:J Clin Invest
Päätekijät: Zapf, J, Futo, E, Peter, M, Froesch, E R
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Clinical Investigation 1992
Aiheet:
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC443417/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1281841/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116152
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