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Regulation of binding proteins for insulin-like growth factors (IGF) in humans. Increased expression of IGF binding protein 2 during IGF I treatment of healthy adults and in patients with extrapancreatic tumor hypoglycemia.

Insulin-like growth factors (IGFs) in blood form two complexes with specific binding proteins (BPs): a large, growth hormone (GH)-dependent complex with restricted capillary permeability, and a smaller complex, inversely related to GH, with high turnover of its IGF pool and free capillary permeabili...

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Bibliographic Details
Published in:J Clin Invest
Main Authors: Zapf, J, Schmid, C, Guler, H P, Waldvogel, M, Hauri, C, Futo, E, Hossenlopp, P, Binoux, M, Froesch, E R
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 1990
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296815/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1697608/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114797
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