Can "big" insulin-like growth factor II in serum of tumor patients account for the development of extrapancreatic tumor hypoglycemia?

The pathogenesis of extrapancreatic tumor hypoglycemia has been related to the secretion of big insulin-like growth factor (IGF) II by the tumor. In 25 of 28 patients with this type of hypoglycemia we found 1.5-8-fold elevated serum levels of immunoreactive big (15-25 kD), but decreased levels of no...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Zapf, J, Futo, E, Peter, M, Froesch, E R
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC443417/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1281841/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116152
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