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()Platelet-driven leukotriene C(4)-mediated airway inflammation in mice is aspirin-sensitive and depends on T prostanoid receptors
Cysteinyl leukotrienes (cysLTs) are bronchoconstricting lipid mediators that amplify eosinophilic airway inflammation by incompletely understood mechanisms. We recently found that leukotriene C(4) (LTC(4)), the parent cysLT, potently activates platelets in vitro and induces airway eosinophilia in al...
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| Publicado no: | J Immunol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4433852/ https://ncbi.nlm.nih.gov/pubmed/25904552 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402959 |
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