MATURE CYSTIC FIBROSIS AIRWAY NEUTROPHILS SUPPRESS T-CELL FUNCTION: EVIDENCE FOR A ROLE OF ARGINASE 1, BUT NOT PROGRAMMED DEATH-LIGAND 1

Bacteria colonize cystic fibrosis (CF) airways, and while T cells with appropriate antigen specificity are present in draining lymph nodes, they are conspicuously absent from the lumen. To account for this absence, we hypothesized that polymorphonuclear neutrophils (PMNs), recruited massively into t...

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Bibliografische gegevens
Gepubliceerd in:J Immunol
Hoofdauteurs: Ingersoll, Sarah A., Laval, Julie, Forrest, Osric A., Preininger, Marcela, Brown, Milton R., Arafat, Dalia, Gibson, Greg, Tangpricha, Vin, Tirouvanziam, Rabindra
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4433848/
https://ncbi.nlm.nih.gov/pubmed/25926674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500312
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