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Profound functional and signaling changes in viable inflammatory neutrophils homing to cystic fibrosis airways

Blood neutrophils recruited to cystic fibrosis (CF) airways are believed to be rapidly killed by resident bacteria and to passively release elastase and other toxic by-products that promote disease progression. By single-cell analysis, we demonstrate that profound functional and signaling changes re...

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Auteurs principaux: Tirouvanziam, Rabindra, Gernez, Yael, Conrad, Carol K., Moss, Richard B., Schrijver, Iris, Dunn, Colleen E., Davies, Zoe A., Herzenberg, Leonore A., Herzenberg, Leonard A.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2008
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2393742/
https://ncbi.nlm.nih.gov/pubmed/18334635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0712386105
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