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High-dose oral N-acetylcysteine, a glutathione prodrug, modulates inflammation in cystic fibrosis
Neutrophilic airway inflammation is a hallmark of cystic fibrosis (CF). As high oxidant producers, airway neutrophils contribute largely to the systemic redox imbalance seen in CF. In turn, this chronic and profound imbalance can impact circulating neutrophils before their migration into airways. In...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2006
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1450222/ https://ncbi.nlm.nih.gov/pubmed/16537378 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0511304103 |
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