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High-dose oral N-acetylcysteine, a glutathione prodrug, modulates inflammation in cystic fibrosis

Neutrophilic airway inflammation is a hallmark of cystic fibrosis (CF). As high oxidant producers, airway neutrophils contribute largely to the systemic redox imbalance seen in CF. In turn, this chronic and profound imbalance can impact circulating neutrophils before their migration into airways. In...

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Detalhes bibliográficos
Main Authors: Tirouvanziam, Rabindra, Conrad, Carol K., Bottiglieri, Teodoro, Herzenberg, Leonore A., Moss, Richard B., Herzenberg, Leonard A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1450222/
https://ncbi.nlm.nih.gov/pubmed/16537378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0511304103
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