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Hypercapnia Inhibits Autophagy and Bacterial Killing in Human Macrophages by Increasing Expression of Bcl-2 and Bcl-xL
Hypercapnia, the elevation of CO(2) in blood and tissue, commonly develops in patients with advanced lung disease and severe pulmonary infections, and is associated with high mortality. We previously reported that hypercapnia alters expression of host defense genes, inhibits phagocytosis, and increa...
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| Опубликовано в: : | J Immunol |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4433787/ https://ncbi.nlm.nih.gov/pubmed/25895534 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500150 |
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