Visual impairment in an optineurin mouse model of primary open angle glaucoma

Primary open angle glaucoma (POAG) is characterized by progressive neurodegeneration of retinal ganglion cells (RGCs). Why RGCs degenerate in low pressure POAG remains poorly understood. To gain mechanistic insights, we developed a novel mouse model based on a mutation in human optineurin associated...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Neurobiol Aging
Päätekijät: Tseng, Henry C., Riday, Thorfinn T., McKee, Celia, Braine, Catherine E, Bomze, Howard, Barak, Ian, Marean-Reardon, Carrie, John, Simon W.M., Philpot, Benjamin D., Ehlers, Michael D.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2015
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4433607/
https://ncbi.nlm.nih.gov/pubmed/25818176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2015.02.012
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