Visual impairment in an optineurin mouse model of primary open angle glaucoma

Primary open angle glaucoma (POAG) is characterized by progressive neurodegeneration of retinal ganglion cells (RGCs). Why RGCs degenerate in low pressure POAG remains poorly understood. To gain mechanistic insights, we developed a novel mouse model based on a mutation in human optineurin associated...

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Detalhes bibliográficos
Publicado no:Neurobiol Aging
Main Authors: Tseng, Henry C., Riday, Thorfinn T., McKee, Celia, Braine, Catherine E, Bomze, Howard, Barak, Ian, Marean-Reardon, Carrie, John, Simon W.M., Philpot, Benjamin D., Ehlers, Michael D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4433607/
https://ncbi.nlm.nih.gov/pubmed/25818176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2015.02.012
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