Visual impairment in an optineurin mouse model of primary open angle glaucoma

Primary open angle glaucoma (POAG) is characterized by progressive neurodegeneration of retinal ganglion cells (RGCs). Why RGCs degenerate in low pressure POAG remains poorly understood. To gain mechanistic insights, we developed a novel mouse model based on a mutation in human optineurin associated...

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Publicat a:Neurobiol Aging
Autors principals: Tseng, Henry C., Riday, Thorfinn T., McKee, Celia, Braine, Catherine E, Bomze, Howard, Barak, Ian, Marean-Reardon, Carrie, John, Simon W.M., Philpot, Benjamin D., Ehlers, Michael D.
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4433607/
https://ncbi.nlm.nih.gov/pubmed/25818176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2015.02.012
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