Tyrosyl radical generated by myeloperoxidase catalyzes the oxidative cross-linking of proteins.

Phagocytes generate H2O2 for use by a secreted heme enzyme, myeloperoxidase, to kill invading bacteria, viruses, and fungi. We have explored the possibility that myeloperoxidase might also convert L-tyrosine to a radical catalyst that cross-links proteins. Protein-bound tyrosyl residues exposed to m...

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Detaylı Bibliyografya
Asıl Yazarlar: Heinecke, J W, Li, W, Francis, G A, Goldstein, J A
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1993
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC443356/
https://ncbi.nlm.nih.gov/pubmed/8390491
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