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Humoral Immunity in the Gut Selectively Targets Phenotypically Virulent Attaching-and-Effacing Bacteria for Intraluminal Elimination

Virulence factors expressed by enteric bacteria are pivotal for pathogen colonization and induction of intestinal disease, but the mechanisms by which host immunity regulates pathogen virulence are largely unknown. Here we show that specific antibody responses are required for down-regulation of vir...

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Bibliografiske detaljer
Udgivet i:Cell Host Microbe
Main Authors: Kamada, Nobuhiko, Sakamoto, Kei, Seo, Sang-Uk, Zeng, Melody Y., Kim, Yun-Gi, Cascalho, Marilia, Vallance, Bruce A., Puente, José L., Núñez, Gabriel
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4433422/
https://ncbi.nlm.nih.gov/pubmed/25936799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2015.04.001
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