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Regulated Virulence Controls the Ability of a Pathogen to Compete with the Gut Microbiota

The virulence mechanisms that allow pathogens to colonize the intestine remain unclear. Here we show that germ-free animals are unable to eradicate Citrobacter rodentium, a model for human infections with attaching/effacing bacteria. Early in infection, virulence genes were expressed and required fo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kamada, Nobuhiko, Kim, Yun-Gi, Sham, Ho Pan, Vallance, Bruce A., Puente, José L., Martens, Eric C., Núñez, Gabriel
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3439148/
https://ncbi.nlm.nih.gov/pubmed/22582016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1222195
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