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Regulated Virulence Controls the Ability of a Pathogen to Compete with the Gut Microbiota

The virulence mechanisms that allow pathogens to colonize the intestine remain unclear. Here we show that germ-free animals are unable to eradicate Citrobacter rodentium, a model for human infections with attaching/effacing bacteria. Early in infection, virulence genes were expressed and required fo...

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Autori principali: Kamada, Nobuhiko, Kim, Yun-Gi, Sham, Ho Pan, Vallance, Bruce A., Puente, José L., Martens, Eric C., Núñez, Gabriel
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3439148/
https://ncbi.nlm.nih.gov/pubmed/22582016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1222195
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