The ability of an attaching and effacing pathogen to trigger localized actin assembly contributes to virulence by promoting mucosal attachment

Enterohemorrhagic Escherichia coli (EHEC) adheres to intestinal epithelial cells, then stimulates the actin nucleation promoting factor N-WASP to induce localized actin assembly resulting in an actin “pedestal”, the function of which is poorly understood. EHEC also produces Shiga toxin (Stx), which...

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Autors principals: Mallick, Emily M., Garber, John J., Vanguri, Vijay K., Balasubramanian, Sowmya, Blood, Timothy, Clark, Stacie, Vingadassalom, Didier, Louissaint, Christopher, McCormick, Beth, Snapper, Scott B., Leong, John M.
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4146666/
https://ncbi.nlm.nih.gov/pubmed/24780054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cmi.12302
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