The ability of an attaching and effacing pathogen to trigger localized actin assembly contributes to virulence by promoting mucosal attachment

Enterohemorrhagic Escherichia coli (EHEC) adheres to intestinal epithelial cells, then stimulates the actin nucleation promoting factor N-WASP to induce localized actin assembly resulting in an actin “pedestal”, the function of which is poorly understood. EHEC also produces Shiga toxin (Stx), which...

Full description

Saved in:
Bibliographic Details
Main Authors: Mallick, Emily M., Garber, John J., Vanguri, Vijay K., Balasubramanian, Sowmya, Blood, Timothy, Clark, Stacie, Vingadassalom, Didier, Louissaint, Christopher, McCormick, Beth, Snapper, Scott B., Leong, John M.
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4146666/
https://ncbi.nlm.nih.gov/pubmed/24780054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cmi.12302
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items