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Production of clastogenic DNA precursors by the nucleotide metabolism in Escherichia coli
RdgB is a bacterial dNTPase with a strong in vitro preference for non-canonical DNA precursors dHapTP, dXTP and dITP that contain deaminated or aminogroup-modified purines. Utilization of these nucleotides by replisomes in rdgB mutants of E. coli produces modified DNA, on which EndoV-nicking near th...
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| Veröffentlicht in: | Mol Microbiol |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4433007/ https://ncbi.nlm.nih.gov/pubmed/19943897 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2009.06994.x |
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