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Hypoxanthine Incorporation Is Nonmutagenic in Escherichia coli

Endonuclease V, encoded by the nfi gene, initiates removal of the base analogs hypoxanthine and xanthine from DNA, acting to prevent mutagenesis from purine base deamination within the DNA. On the other hand, the RdgB nucleotide hydrolase in Escherichia coli is proposed to prevent hypoxanthine and x...

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Detalhes bibliográficos
Main Authors: Budke, Brian, Kuzminov, Andrei
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1595496/
https://ncbi.nlm.nih.gov/pubmed/16952947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00447-06
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