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Hypoxanthine Incorporation Is Nonmutagenic in Escherichia coli

Endonuclease V, encoded by the nfi gene, initiates removal of the base analogs hypoxanthine and xanthine from DNA, acting to prevent mutagenesis from purine base deamination within the DNA. On the other hand, the RdgB nucleotide hydrolase in Escherichia coli is proposed to prevent hypoxanthine and x...

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Autori principali: Budke, Brian, Kuzminov, Andrei
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1595496/
https://ncbi.nlm.nih.gov/pubmed/16952947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00447-06
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