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Low molecular weight DNA replication intermediates in Escherichia coli: mechanism of formation and strand specificity

Chromosomal DNA replication intermediates, revealed in ligase-deficient conditions in vivo, are of low molecular weight independently of the organism, suggesting discontinuous replication of both the leading and the lagging DNA strands. Yet, in vitro experiments with purified enzymes replicating sig...

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Detalhes bibliográficos
Main Authors: Amado, Luciana, Kuzminov, Andrei
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3812275/
https://ncbi.nlm.nih.gov/pubmed/23876705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2013.07.021
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