Toll-Like Receptor 2-Dependent Extracellular Signal-Regulated Kinase Signaling in Mycobacterium tuberculosis-Infected Macrophages Drives Anti-Inflammatory Responses and Inhibits Th1 Polarization of Responding T Cells

Mycobacterium tuberculosis survives within macrophages and employs immune evasion mechanisms to persist in the host. Protective T helper type 1 (Th1) responses are induced, and the immune response in most individuals is sufficient to restrict M. tuberculosis to latent infection, but most infections...

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Xehetasun bibliografikoak
Argitaratua izan da:Infect Immun
Egile Nagusiak: Richardson, Edward T., Shukla, Supriya, Sweet, David R., Wearsch, Pamela A., Tsichlis, Philip N., Boom, W. Henry, Harding, Clifford V.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2015
Gaiak:
Microbial Immunity and Vaccines
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4432743/
https://ncbi.nlm.nih.gov/pubmed/25776754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00135-15
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