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Intraglomerular pressure and mesangial stretching stimulate extracellular matrix formation in the rat.

To define the interplay of glomerular hypertension and hypertrophy with mesangial extracellular matrix (ECM) deposition, we examined the effects of glomerular capillary distention and mesangial cell stretching on ECM synthesis. The volume of microdissected rat glomeruli (Vg), perfused ex vivo at inc...

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Main Authors: Riser, B L, Cortes, P, Zhao, X, Bernstein, J, Dumler, F, Narins, R G
格式: Artigo
語言:Inglês
出版: 1992
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC443255/
https://ncbi.nlm.nih.gov/pubmed/1430216
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