Angiotensin II stimulates extracellular matrix protein synthesis through induction of transforming growth factor-beta expression in rat glomerular mesangial cells.

Angiotensin II (Ang II) has been implicated in the development of progressive glomerulosclerosis, but the precise mechanism of this effect remains unclear. In an experimental model, we have shown previously that TGF-beta plays a key role in glomerulosclerosis by stimulating extracellular matrix prot...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Kagami, S, Border, W A, Miller, D E, Noble, N A
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1994
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC294451/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8200978/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117251
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