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Mechanism of hypertriglyceridemia in human apolipoprotein (apo) CIII transgenic mice. Diminished very low density lipoprotein fractional catabolic rate associated with increased apo CIII and reduced apo E on the particles.

Hypertriglyceridemia is common in the general population, but its mechanism is largely unknown. In previous work human apo CIII transgenic (HuCIIITg) mice were found to have elevated triglyceride levels. In this report, the mechanism for the hypertriglyceridemia was studied. Two different HuCIIITg m...

詳細記述

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書誌詳細
出版年:J Clin Invest
主要な著者: Aalto-Setälä, K, Fisher, E A, Chen, X, Chajek-Shaul, T, Hayek, T, Zechner, R, Walsh, A, Ramakrishnan, R, Ginsberg, H N, Breslow, J L
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 1992
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC443250/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1430212/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116066
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