An interaction between the human cholesteryl ester transfer protein (CETP) and apolipoprotein A-I genes in transgenic mice results in a profound CETP-mediated depression of high density lipoprotein cholesterol levels.

We have previously described two transgenic mouse lines, one heterozygous for the human apo A-I gene and the other heterozygous for a human cholesteryl ester transfer protein (CETP) minigene driven by the mouse metallothionein-I gene promoter. In the current study, these two lines were crossed produ...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Hayek, T, Chajek-Shaul, T, Walsh, A, Agellon, L B, Moulin, P, Tall, A R, Breslow, J L
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1992
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC443127/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1644921/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115887
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