An interaction between the human cholesteryl ester transfer protein (CETP) and apolipoprotein A-I genes in transgenic mice results in a profound CETP-mediated depression of high density lipoprotein cholesterol levels.

We have previously described two transgenic mouse lines, one heterozygous for the human apo A-I gene and the other heterozygous for a human cholesteryl ester transfer protein (CETP) minigene driven by the mouse metallothionein-I gene promoter. In the current study, these two lines were crossed produ...

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Détails bibliographiques
Auteurs principaux: Hayek, T, Chajek-Shaul, T, Walsh, A, Agellon, L B, Moulin, P, Tall, A R, Breslow, J L
Format: Artigo
Langue:Inglês
Publié: 1992
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC443127/
https://ncbi.nlm.nih.gov/pubmed/1644921
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