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Therapeutic approaches for HER2-positive brain metastases: Circumventing the blood–brain barrier

We aim to summarize data from studies of trastuzumab in patients with human epidermal growth factor receptor 2 (HER2)–positive metastatic breast cancer (MBC) and brain metastasis and to describe novel methods being developed to circumvent the blood–brain barrier (BBB). A literature search was conduc...

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Detalhes bibliográficos
Publicado no:Cancer Treat Rev
Main Authors: Mehta, Ankit I., Brufsky, Adam M., Sampson, John H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4432469/
https://ncbi.nlm.nih.gov/pubmed/22727691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ctrv.2012.05.006
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