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Promising approaches to circumvent the blood-brain barrier: progress, pitfalls and clinical prospects in brain cancer
Brain drug delivery is a major challenge for therapy of central nervous system (CNS) diseases. Biochemical modifications of drugs or drug nanocarriers, methods of local delivery, and blood–brain barrier (BBB) disruption with focused ultrasound and microbubbles are promising approaches which enhance...
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| Publicado no: | Ther Deliv |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4618388/ https://ncbi.nlm.nih.gov/pubmed/26488496 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/tde.15.48 |
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