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Drug resistance in HER2-positive breast cancer brain metastases: blame the barrier or the brain?

The brain is the most common site of first metastasis for patients with HER2-positive breast cancer treated with HER2-targeting drugs. However, the development of effective therapies for breast cancer brain metastases (BCBMs) is limited by an incomplete understanding of the mechanisms governing drug...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Kabraji, Sheheryar, Ni, Jing, Lin, Nancy U., Xie, Shaozhen, Winer, Eric P., Zhao, Jean J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5899637/
https://ncbi.nlm.nih.gov/pubmed/29437794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-17-3351
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