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Heterotrimeric Kinesin-2 (KIF3) Mediates Transition Zone and Axoneme Formation of Mouse Photoreceptors

Anterograde intraflagellar transport (IFT) employing kinesin-2 molecular motors has been implicated in trafficking of photoreceptor outer segment proteins. We generated embryonic retina-specific (prefix “emb”) and adult tamoxifen-induced (prefix “tam”) deletions of KIF3a and IFT88 in adult mice to s...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Jiang, Li, Wei, Yuxiao, Ronquillo, Cecinio C., Marc, Robert E., Yoder, Bradley K., Frederick, Jeanne M., Baehr, Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4432293/
https://ncbi.nlm.nih.gov/pubmed/25825494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.638437
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