Deletion of the phosphatase INPP5E in the murine retina impairs photoreceptor axoneme formation and prevents disc morphogenesis

INPP5E, also known as pharbin, is a ubiquitously expressed phosphatidylinositol polyphosphate 5-phosphatase that is typically located in the primary cilia and modulates the phosphoinositide composition of membranes. Mutations to or loss of INPP5E is associated with ciliary dysfunction. INPP5E missen...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Sharif, Ali S., Gerstner, Cecilia D., Cady, Martha A., Arshavsky, Vadim Y., Mitchell, Christina, Ying, Guoxin, Frederick, Jeanne M., Baehr, Wolfgang
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2021
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8047226/
https://ncbi.nlm.nih.gov/pubmed/33711342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100529
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