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Trafficking of Membrane Proteins to Cone But Not Rod Outer Segments Is Dependent on Heterotrimeric Kinesin-II

Heterotrimeric kinesin-II is a molecular motor localized to the inner segment, connecting cilium and axoneme of mammalian photoreceptors. Our purpose was to identify the role of kinesin-II in anterograde intraflagellar transport by photoreceptor-specific deletions of kinesin family member 3A (KIF3A)...

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Autori principali: Avasthi, Prachee, Watt, Carl B., Williams, David S., Le, Yun Z., Li, Sha, Chen, Ching-Kang, Marc, Robert E., Frederick, Jeanne M., Baehr, Wolfgang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2788486/
https://ncbi.nlm.nih.gov/pubmed/19906976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3976-09.2009
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