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In Vitro Antimalarial Activity of Novel Semisynthetic Nocathiacin I Antibiotics

Presently, the arsenal of antimalarial drugs is limited and needs to be replenished. We evaluated the potential antimalarial activity of two water-soluble derivatives of nocathiacin (BMS461996 and BMS411886) against the asexual blood stages of Plasmodium falciparum. Nocathiacins are a thiazolyl pept...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Sharma, Indu, Sullivan, Margery, McCutchan, Thomas F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4432204/
https://ncbi.nlm.nih.gov/pubmed/25779576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04294-14
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