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Squalestatin Is an Inhibitor of Carotenoid Biosynthesis in Plasmodium falciparum

The increasing resistance of malaria parasites to almost all available drugs calls for the characterization of novel targets and the identification of new compounds. Carotenoids are polyisoprenoids from plants, algae, and some bacteria, and they are biosynthesized by Plasmodium falciparum but not by...

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Bibliografske podrobnosti
izdano v:Antimicrob Agents Chemother
Main Authors: Gabriel, Heloisa B., Silva, Marcia F., Kimura, Emília A., Wunderlich, Gerhard, Katzin, Alejandro M., Azevedo, Mauro F.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4432196/
https://ncbi.nlm.nih.gov/pubmed/25779575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04500-14
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