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Squalestatin Is an Inhibitor of Carotenoid Biosynthesis in Plasmodium falciparum

The increasing resistance of malaria parasites to almost all available drugs calls for the characterization of novel targets and the identification of new compounds. Carotenoids are polyisoprenoids from plants, algae, and some bacteria, and they are biosynthesized by Plasmodium falciparum but not by...

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Publicat a:Antimicrob Agents Chemother
Autors principals: Gabriel, Heloisa B., Silva, Marcia F., Kimura, Emília A., Wunderlich, Gerhard, Katzin, Alejandro M., Azevedo, Mauro F.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4432196/
https://ncbi.nlm.nih.gov/pubmed/25779575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04500-14
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