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Squalestatin Is an Inhibitor of Carotenoid Biosynthesis in Plasmodium falciparum

The increasing resistance of malaria parasites to almost all available drugs calls for the characterization of novel targets and the identification of new compounds. Carotenoids are polyisoprenoids from plants, algae, and some bacteria, and they are biosynthesized by Plasmodium falciparum but not by...

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書目詳細資料
發表在:Antimicrob Agents Chemother
Main Authors: Gabriel, Heloisa B., Silva, Marcia F., Kimura, Emília A., Wunderlich, Gerhard, Katzin, Alejandro M., Azevedo, Mauro F.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4432196/
https://ncbi.nlm.nih.gov/pubmed/25779575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04500-14
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