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Terpenes Arrest Parasite Development and Inhibit Biosynthesis of Isoprenoids in Plasmodium falciparum

Development of new drugs is one of the strategies for malaria control. The biosynthesis of several isoprenoids in Plasmodium falciparum was recently described. Interestingly, some intermediates and final products biosynthesized by this pathway in mammals differ from those biosynthesized in P. falcip...

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Detalhes bibliográficos
Main Authors: Rodrigues Goulart, Herbert, Kimura, Emília A., Peres, Valnice J., Couto, Alicia S., Aquino Duarte, Fulgencio A., Katzin, Alejandro M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC434199/
https://ncbi.nlm.nih.gov/pubmed/15215101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.7.2502-2509.2004
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