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In Vivo Cluster Formation of Nisin and Lipid II Is Correlated with Membrane Depolarization
Nisin and related lantibiotics kill bacteria by pore formation or by sequestering lipid II. Some lantibiotics sequester lipid II into clusters, which were suggested to kill cells through delocalized peptidoglycan synthesis. Here, we show that cluster formation is always concomitant with (i) membrane...
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| Publicado no: | Antimicrob Agents Chemother |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4432147/ https://ncbi.nlm.nih.gov/pubmed/25870072 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04781-14 |
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