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In Vivo Cluster Formation of Nisin and Lipid II Is Correlated with Membrane Depolarization

Nisin and related lantibiotics kill bacteria by pore formation or by sequestering lipid II. Some lantibiotics sequester lipid II into clusters, which were suggested to kill cells through delocalized peptidoglycan synthesis. Here, we show that cluster formation is always concomitant with (i) membrane...

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Detaylı Bibliyografya
Yayımlandı:Antimicrob Agents Chemother
Asıl Yazarlar: Tol, Menno B., Morales Angeles, Danae, Scheffers, Dirk-Jan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4432147/
https://ncbi.nlm.nih.gov/pubmed/25870072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04781-14
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