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Achieving Target Voriconazole Concentrations More Accurately in Children and Adolescents
Despite the documented benefit of voriconazole therapeutic drug monitoring, nonlinear pharmacokinetics make the timing of steady-state trough sampling and appropriate dose adjustments unpredictable by conventional methods. We developed a nonparametric population model with data from 141 previously r...
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| Publicado no: | Antimicrob Agents Chemother |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4432122/ https://ncbi.nlm.nih.gov/pubmed/25779580 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00032-15 |
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