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Achieving Target Voriconazole Concentrations More Accurately in Children and Adolescents

Despite the documented benefit of voriconazole therapeutic drug monitoring, nonlinear pharmacokinetics make the timing of steady-state trough sampling and appropriate dose adjustments unpredictable by conventional methods. We developed a nonparametric population model with data from 141 previously r...

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書誌詳細
出版年:Antimicrob Agents Chemother
主要な著者: Neely, Michael, Margol, Ashley, Fu, Xiaowei, van Guilder, Michael, Bayard, David, Schumitzky, Alan, Orbach, Regina, Liu, Siyu, Louie, Stan, Hope, William
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4432122/
https://ncbi.nlm.nih.gov/pubmed/25779580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00032-15
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