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Protein structure prediction provides comparable performance to crystallographic structures in docking-based virtual screening

Structure based virtual screening has largely been limited to protein targets for which either an experimental structure is available or a strongly homologous template exists so that a high-resolution model can be constructed. The performance of state of the art protein structure predictions in virt...

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Detalhes bibliográficos
Publicado no:Methods
Main Authors: Du, Hongying, Brender, Jeffrey R., Zhang, Jian, Zhang, Yang
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4431978/
https://ncbi.nlm.nih.gov/pubmed/25220914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2014.08.017
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