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Computational protein-ligand docking and virtual drug screening with the AutoDock suite

Computational docking can be used to predict bound conformations and free energies of binding for small molecule ligands to macromolecular targets. Docking is widely used for the study of biomolecular interactions and mechanisms, and is applied to structure-based drug design. The methods are fast en...

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Detalhes bibliográficos
Publicado no:Nat Protoc
Main Authors: Forli, Stefano, Huey, Ruth, Pique, Michael E., Sanner, Michel, Goodsell, David S., Olson, Arthur J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4868550/
https://ncbi.nlm.nih.gov/pubmed/27077332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2016.051
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