Loading...

ATM couples replication stress and metabolic reprogramming during cellular senescence

Replication stress induced by nucleotide deficiency plays an important role in cancer initiation. Replication stress in primary cells typically activates the cellular senescence tumor suppression mechanism. Senescence bypass correlates with development of cancer, a disease characterized by metabolic...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Cell Rep
Main Authors: Aird, Katherine M., Worth, Andrew J., Snyder, Nathaniel W., Lee, Joyce V., Sivanand, Sharanya, Liu, Qin, Blair, Ian A., Wellen, Kathryn E., Zhang, Rugang
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4431925/
https://ncbi.nlm.nih.gov/pubmed/25937285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.04.014
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!