ATM couples replication stress and metabolic reprogramming during cellular senescence

Replication stress induced by nucleotide deficiency plays an important role in cancer initiation. Replication stress in primary cells typically activates the cellular senescence tumor suppression mechanism. Senescence bypass correlates with development of cancer, a disease characterized by metabolic...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Cell Rep
Autors principals: Aird, Katherine M., Worth, Andrew J., Snyder, Nathaniel W., Lee, Joyce V., Sivanand, Sharanya, Liu, Qin, Blair, Ian A., Wellen, Kathryn E., Zhang, Rugang
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4431925/
https://ncbi.nlm.nih.gov/pubmed/25937285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.04.014
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars