Smad 1/5 and Smad 4 Expression Are Important for Osteoclast Differentiation

To investigate the necessity of the canonical BMP pathway during osteoclast differentiation, we created osteoclasts with a conditional gene deletion for Smad1 and Smad5 (SMAD1/5), or Smad4 using adenovirus expressing CRE recombinase (Ad-CRE). Reduction of either Smad4 or Smad1/5 expression resulted...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:J Cell Biochem
Hlavní autoři: Tasca, Amy, Stemig, Melissa, Broege, Aaron, Huang, Brandon, Davydova, Julia, Zwijsen, An, Umans, Lieve, Jensen, Eric D., Gopalakrishnan, Raj, Mansky, Kim C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4431909/
https://ncbi.nlm.nih.gov/pubmed/25711193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.25092
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky