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Smad 1/5 and Smad 4 Expression Are Important for Osteoclast Differentiation
To investigate the necessity of the canonical BMP pathway during osteoclast differentiation, we created osteoclasts with a conditional gene deletion for Smad1 and Smad5 (SMAD1/5), or Smad4 using adenovirus expressing CRE recombinase (Ad-CRE). Reduction of either Smad4 or Smad1/5 expression resulted...
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| Publicado no: | J Cell Biochem |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4431909/ https://ncbi.nlm.nih.gov/pubmed/25711193 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.25092 |
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