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Dichotomy of Genetic Abnormalities in PEComas with Therapeutic Implications
Perivascular epithelioid cell neoplasms (PEComa) are a family of rare mesenchymal tumors with hybrid myo-melanocytic differentiation. Although most PEComas harbor loss of function TSC1/TSC2 mutations, a small subset were reported to carry TFE3 gene rearrangements. As no comprehensive genomic study h...
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Опубликовано в: : | Am J Surg Pathol |
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Главные авторы: | , , , , , , , , |
Формат: | Artigo |
Язык: | Inglês |
Опубликовано: |
2015
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Предметы: | |
Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4431898/ https://ncbi.nlm.nih.gov/pubmed/25651471 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PAS.0000000000000389 |
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