Dichotomy of Genetic Abnormalities in PEComas with Therapeutic Implications

Perivascular epithelioid cell neoplasms (PEComa) are a family of rare mesenchymal tumors with hybrid myo-melanocytic differentiation. Although most PEComas harbor loss of function TSC1/TSC2 mutations, a small subset were reported to carry TFE3 gene rearrangements. As no comprehensive genomic study h...

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Detalhes bibliográficos
Publicado no:Am J Surg Pathol
Main Authors: Agaram, Narasimhan P, Sung, Yun-Shao, Zhang, Lei, Chen, Chun-Liang, Chen, Hsiao-Wei, Singer, Samuel, Dickson, Mark A., Berger, Michael F., Antonescu, Cristina R
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4431898/
https://ncbi.nlm.nih.gov/pubmed/25651471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PAS.0000000000000389
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