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Secondary EWSR1 Gene Abnormalities in SMARCB1-Deficient Tumors with 22q11-12 Regional Deletions: Potential Pitfalls in Interpreting EWSR1 FISH Results

SMARCB1 inactivation occurs in a variety of tumors, being caused by various genetic mechanisms. Since SMARCB1 and EWSR1 genes are located close to each other on chromosome 22, larger SMARCB1 deletions may encompass the EWSR1 locus. Herein, we report four cases with SMARCB1-deletions showing concurre...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Genes Chromosomes Cancer
Prif Awduron: Huang, Shih-Chiang, Zhang, Lei, Sung, Yun-Shao, Chen, Chun-Liang, Kao, Yu-Chien, Agaram, Narasimhan P., Antonescu, Cristina R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5006943/
https://ncbi.nlm.nih.gov/pubmed/27218413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gcc.22376
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