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Congenital Anomalies and Rhabdoid Tumor Associated with 22q11 Germline Deletion and Somatic Inactivation of the SMARCB1 Tumor Suppressor

The most common microdeletion in humans involves the 22q11 region. Congenital anomalies associated with 22q11 loss include cardiac and facial defects. Less frequent is the co-presentation of malignant rhabdoid tumors that are highly aggressive childhood malignancies typically found in renal or extra...

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Detalhes bibliográficos
Main Authors: Toth, George, Zraly, Claudia B., Thomson, Tricia L., Jones, Carolyn, Lapetino, Shawn, Muraskas, Jonathan, Zhang, Jiwang, Dingwall, Andrew K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3075385/
https://ncbi.nlm.nih.gov/pubmed/21412926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gcc.20862
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