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Identification of Sestrin3 Involved in the In vitro Resistance of Colorectal Cancer Cells to Irinotecan

Irinotecan, an analogue of camptothecin, is frequently used as a single agent or in combination with other anticancer drugs for the treatment of colorectal cancer. However, the drug resistance of tumors is a major obstacle to successful cancer treatment. In this study, we established that cells acqu...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Choi, Seung Ho, Hong, Hye Kyung, Cho, Yong Beom, Lee, Woo Yong, Yoo, Hae Yong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4431826/
https://ncbi.nlm.nih.gov/pubmed/25973791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0126830
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